SARS-CoV-2 Mpro-IN-31
CAT:
804-HY-168599
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SARS-CoV-2 Mpro-IN-31
- CAS Number: 870153-73-4
- UNSPSC Description: SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 value of 11 nM. Additionally, SARS-CoV-2 Mpro-IN-31 effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively[1].
- Target Antigen: SARS-CoV
- Type: Reference compound
- Related Pathways: Anti-infection
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/sars-cov-2-mpro-in-31.html
- Smiles: COC1=C2C=C(NC2=CC=C1)C(N[C@H](C(N[C@H](C(COC(C3=C(C=CC=C3Cl)Cl)=O)=O)C[C@@H]4CCNC4=O)=O)CC(C)C)=O
- Molecular Weight: 645.53
- References & Citations: [1]Poli A N R, et al. Design of novel and highly selective SARS-CoV-2 main protease inhibitors[J]. Antimicrobial Agents and Chemotherapy, 2024, 68(10): e00562-24.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported