Antitubercular agent 34

• Description:

  Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-34.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NOC(C2=CSC(NC3=CC=CC=C3)=N2)=C1)NC4=CC=CC=C4

• Molecular Formula:

  C19H14N4O2S

• Molecular Weight:

  362.41

• References & Citations:

  [1]Girardini M, et al. Expanding the knowledge around antitubercular 5- (2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114916.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2883173-23-5]