TGFβ1-IN-3

• UNSPSC Description:

  TGFβ1-IN-3 is a diarylacylhydrazones derivative that effectively suppresses the activation and proliferation of fibroblasts. TGFβ1-IN-3 can be used for idiopathic pulmonary fibrosis (IPF) research[1].

• Target Antigen:

  TGF-β Receptor

• Type:

  Reference compound

• Related Pathways:

  TGF-beta/Smad

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/tgfβ1-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C=C1)OCCCCCCN2CCCCC2)N/N=C/C3=CC=C(O3)[N+]([O-])=O

• Molecular Weight:

  442.51

• References & Citations:

  [1]Xingping Su, et al. Design, synthesis and biological evaluation of novel diarylacylhydrazones derivatives for the efficient treatment of idiopathic pulmonary fibrosis. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114918.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2883813-58-7