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DACN (Tos) (hydrochloride)

CAT: 0804-HY-151795Size: 1 EachDry Ice: NoHazardous: No
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Description
DACN (Tos) hydrochloride is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions, such strain-promoted azide-alkyne cycloadditions (SPAAC) by using cycloalkynes. DACNs possesses high thermal and chemical stability along with comparable click reactivity. DACN (Tos) hydrochloride can be used for the research of molecular conjugation[1].
CAS Number
2331322-18-8
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dacn-tos-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C)C=C1)(N2CC#CCNCCC2)=O.Cl
Molecular Formula
C14H19ClN2O2S
Molecular Weight
314.83
References & Citations
[1]Kawasaki, et al. Synthesis of NMs-DACN: Small and Hydrophilic Click Reaction Device. Chemistry Letters. Volume: 48. Issue: 5. Pages: 495-497. Journal. 2019.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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