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DACN (Tos2)

CAT: 0804-HY-151697Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151697Size:1 Each
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Description
DACN (Tos2) is a a click chemistry reagent containing an cycloalkynes group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. DACN (Tos2) through such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes. DACN (Tos2) can be used for the research of molecular conjugation[1].
CAS Number
1797508-57-6
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dacn-tos2.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C)C=C1)(N2CC#CCN(S(=O)(C3=CC=C(C)C=C3)=O)CCC2)=O
Molecular Formula
C21H24N2O4S2
Molecular Weight
432.56
References & Citations
[1]gawa, Kazunobu, et al. Thieme Chemistry Journals Awardees: Where Are They Now? One-Pot Synthesis of Versatile Buckle Units for Click Chemistry: 4,8-Diazacyclononynes (DACNs) . Synlett. Volume: 28. Issue: 16. Pages: 2110-2114. Journal. 2017.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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