DACN(Tos2)

• CAS Number:

  1797508-57-6

• UNSPSC Description:

  DACN(Tos2) is a a click chemistry reagent containing an cycloalkynes group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. DACN(Tos2) through such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes. DACN(Tos2) can be used for the research of molecular conjugation[1].

• Target Antigen:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dacn-tos2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=S(C1=CC=C(C)C=C1)(N2CC#CCN(S(=O)(C3=CC=C(C)C=C3)=O)CCC2)=O

• Molecular Weight:

  432.56

• References & Citations:

  [1]gawa, Kazunobu, et al. Thieme Chemistry Journals Awardees: Where Are They Now? One-Pot Synthesis of Versatile Buckle Units for Click Chemistry: 4,8-Diazacyclononynes (DACNs). Synlett. Volume: 28. Issue: 16. Pages: 2110-2114. Journal. 2017.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported