H-L-Tyr(3-N3)-OH

H-L-Tyr(3-N3)-OH

• CAS Number: 129960-90-3
• UNSPSC Description: H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1]. H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/h-l-tyr-3-n3-oh.html
• Solubility: 10 mM in DMSO
• Smiles: OC([C@@H](N)CC1=CC(N=[N+]=[N-])=C(C=C1)O)=O
• Molecular Weight: 222.20
• References & Citations: [1]Yokogawa T, et al. Incorporation of 3-azidotyrosine into proteins through engineering yeast tyrosyl-tRNA synthetase and its application to site-selective protein modification. Methods Mol Biol. 2010;607:227-42.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported