H-L-Orn(N3)-OH (hydrochloride)

• UNSPSC Description:

  H-L-Orn(N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. H-L-Orn(N3)-OH (hydrochloride) can be used for the research of various biochemical[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

• Target Antigen:

  ADC Linker

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/h-l-orn-n3-oh-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [N-]=[N+]=NCCC[C@H](N)C(O)=O.Cl

• Molecular Weight:

  194.62

• References & Citations:

  [1]Ye Wu, et al. A novel peptide stapling strategy enables the retention of ring-closing amino acid side chains for the Wnt/β-catenin signalling pathway. Chem Sci. 2017 Nov 1;8(11):7368-7373.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported