MraY-IN-3

• Description:

  MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC50 value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC50 values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/mray-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCC(N(C1=CC(OCC2=CC=CC=C2)=C(C=C1)C(N[C@H](C(OC)=O)CCCCN)=O)CC3=CC=CC=C3)=O

• Molecular Formula:

  C35H45N3O5

• Molecular Weight:

  587.75

• References & Citations:

  [1]Rachel V Kerr, et al. Peptidomimetic analogues of an Arg-Trp-x-x-Trp motif responsible for interaction of translocase MraY with bacteriophage ϕX174 lysis protein E. Bioorg Med Chem. 2021 Dec 15;52:116502.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2851534-52-4]