MraY-IN-3

MraY-IN-3

• CAS Number: 2851534-52-4
• UNSPSC Description: MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC50 value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC50 values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/mray-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCCCC(N(C1=CC(OCC2=CC=CC=C2)=C(C=C1)C(N[C@H](C(OC)=O)CCCCN)=O)CC3=CC=CC=C3)=O
• Molecular Weight: 587.75
• References & Citations: [1]Rachel V Kerr, et al. Peptidomimetic analogues of an Arg-Trp-x-x-Trp motif responsible for interaction of translocase MraY with bacteriophage ϕX174 lysis protein E. Bioorg Med Chem. 2021 Dec 15;52:116502.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported