Antitubercular agent-31

• Description:

  Antitubercular agent-31 (Compound 2) is an antitubercular agent with an MIC of 0.03 μM against M. tuberculosis H37Rv. Antitubercular agent-31 also inhibits DprE1 with an IC50 of 1.1 μM[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-31.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N=C (N2CCN (CC3CCC (F) (F) CC3) CC2) SC4=C ([N+] ([O-]) =O) C=C (S (=O) (C) =O) C=C14

• Molecular Formula:

  C20H24F2N4O5S2

• Molecular Weight:

  502.56

• References & Citations:

  [1]Shi R, et al. Development of 6-Methanesulfonyl-8-nitrobenzothiazinone Based Antitubercular Agents. ACS Med Chem Lett. 2022 Mar 10;13 (4) :593-598.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2764818-29-1