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PknB-IN-1

CAT: 0804-HY-151204Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151204Size:1 Each
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Description
PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM) . PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL) [1].
CAS Number
1447917-39-6
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pknb-in-1.html
Solubility
10 mM in DMSO
Smiles
CCCCN(CC(CN1C=C(C2=C1C=CC=C2)/C=C/C(C3=CC=CC=C3)=O)O)C
Molecular Formula
C25H30N2O2
Molecular Weight
390.52
References & Citations
[1]Paptawan Thongdee, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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