LasR-IN-2

LasR-IN-2

• CAS Number: 3033530-61-6
• UNSPSC Description: LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF)[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/lasr-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=CC=C1)COC2=CC=C(C3=NC4=CC(Cl)=CC=C4N3)C=C2
• Molecular Weight: 377.82
• References & Citations: [1]Rehab H Abd El-Aleam, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. 2022 Aug 5;241:114629.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported