LasR-IN-1

LasR-IN-1

• CAS Number: 3033530-75-2
• UNSPSC Description: LasR-IN-1 (compound 9g) is a potent LasR inhibitor. LasR-IN-1 has good efficacy toward E. coli. LasR-IN-1 shows anti-bacterial activity, with a MIC of 28.13 μM against P. aeruginosa[1].
• Target Antigen: Bacterial
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/lasr-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(C)C=C1)COC2=CC=C(C3=NC4=CC(C)=CC=C4N3)C=C2
• Molecular Weight: 371.43
• References & Citations: [1]Abd El-Aleam RH, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. 2022 Aug 5;241:114629.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported