β-Glucuronidase/hCAII-IN-1

β-Glucuronidase/hCAII-IN-1

• CAS Number: 2816080-17-6
• UNSPSC Description: β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC50 of 440.1 μM and 4.91 μM, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Cancer; Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/β-glucuronidase-hcaii-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O)OC
• Molecular Weight: 539.49
• References & Citations: [1]Arif N, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H, 5 H-pyrano [3, 2-c] chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. ACS Omega, 2022.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported