hCAII-IN-1

hCAII-IN-1

• CAS Number: 1807520-24-6
• UNSPSC Description: hCAII-IN-1 (compound 7f) is a potent and selective inhibitor of carbonic anhydrase (CA II/IX) with Kis of 1.2 and 113.6 nM, respectively. hCAII-IN-1 has the potential for the research of cancer diseases[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaii-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: NS(=O)(OC1=CC=C(C=C1)NC(N2CCN(CC2)C3=NC(C4=CC=C(C=C4)Br)=CC=N3)=O)=O
• Molecular Weight: 533.40
• References & Citations: [1]Nocentini A, et al. Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors. Eur J Med Chem. 2020;186:111896.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported