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Antiproliferative agent-8

CAT: 0804-HY-147776Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147776Size:1 Each
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Description
Antiproliferative agent-8 (Compound 5a) is an anti-cancer agent. Antiproliferative against-8 has antiproliferative activity. Antiproliferative agent-8 significantly increases the P53 levels[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-8.html
Solubility
10 mM in DMSO
Smiles
CO/C=N\C1=C(C(C2=C(C3=CC=CC=C3N(C2=O)C)O1)C4=CC=C(C=C4)Cl)C#N
Molecular Formula
C22H16ClN3O3
Molecular Weight
405.83
References & Citations
[1]Ramadan M, et al. Design and synthesis of new pyranoquinolinone heteroannulated to triazolopyrimidine of potential apoptotic antiproliferative activity. Bioorg Chem. 2020;105:104392.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported