HDAC6/HSP90-IN-2

• UNSPSC Description:

  HDAC6/HSP90-IN-2 (compound 6e) is a dual inhibitor of HDAC6 and Hsp90, with IC50s of 105.7 and 61 nM, respectively. HDAC6/HSP90-IN-2 can be used for the research of cancer[1].

• Target Antigen:

  Apoptosis; HDAC; HSP

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hdac6-hsp90-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(C(C)C)C=C(C(N(C)CC2=CC=C(C=C2)C(NO)=O)=O)C(O)=C1

• Molecular Weight:

  358.39

• References & Citations:

  [1]Chae HY, et al. Design, synthesis, and biological evalution of bifunctional inhibitors against Hsp90-HDAC6 interplay. Eur J Med Chem. 2022 Jul 6;240:114582.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2803866-22-8