Products for Research Use Only
RegisterLogin

SMO-IN-3

CAT: 0804-HY-150567Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150567Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
CAS Number
2376914-71-3
UNSPSC
12352005
Target
Hedgehog; Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smo-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=CC=C3)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
Molecular Formula
C27H25F4N3O2
Molecular Weight
499.50
References & Citations
[1]Ji D, et al. Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors. Bioorg Med Chem. 2020 Mar 15;28 (6) :115354.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-147743SMO-IN-1
HY-150564-01SMO-IN-2
HY-159893SMO-IN-5
HY-153499SMO-IN-4
HY-110326Smo antagonist M25
HY-P704888-01SMO -VLP, Human (760a.a, HEK293)
HY-P703220SMO, Human (sf9, Flag, His)
HY-RS13443Smo Rat Pre-designed siRNA Set A
HY-RS13442Smo Mouse Pre-designed siRNA Set A
HY-RS13441SMO Human Pre-designed siRNA Set A

Alternative Products

CatalogName
T63387-01SMO-IN-3
528462-01SMO
BZ64354PCMV6-SMO-3*FLAG
PPL00146-3cPLKO.1-SMO shRNA-3
T63429-01SMO-IN-2
T61897-01SMO-IN-1
345945-01Smo discontinued
577224-01SMO (Biotin)
MBS851712-01SMO Antibody
PPL00146SPOTB7-SMO

Popular Products