Antitubercular agent-29

CAT: 0804-HY-150554Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-150554Size:1 Each
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Description
Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS) -Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-29.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4
Molecular Formula
C20H12ClN3O5
Molecular Weight
409.78
References & Citations
[1]Kumar Sahoo S, et al. Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. Bioorg Med Chem. 2022 Jun 15;64:116777.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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