Antitubercular agent-29

• UNSPSC Description:

  Antitubercular agent-29 (compound 6xa) is a potent agent resistant (DR) Mycobacterium tuberculosis (Mtb) inhibitor with MIC of 0.03 μg/mL against agent-susceptible (DS)-Mtb strains, MIC of 0.03-0.06 μg/mL against DR-Mtb strains, and favourable selectivity (SI>40) against Vero cells[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antitubercular-agent-29.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(NC2=NC3=CC(Cl)=CC=C3O2)C=C1)/C=C/C4=CC=C([N+]([O-])=O)O4

• Molecular Weight:

  409.78

• References & Citations:

  [1]Kumar Sahoo S, et al. Identification of nitrofuranylchalcone tethered benzoxazole-2-amines as potent inhibitors of drug resistant Mycobacterium tuberculosis demonstrating bactericidal efficacy. Bioorg Med Chem. 2022 Jun 15;64:116777.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4