(±) -Naproxen-13C, d3

• Description :

  (±) -Naproxen-13C, d3 is the deuterium and 13C labeled (±) -Naproxen[1]. (±) -Naproxen ((Rac) -Naproxen) is a racemate of Naproxen (HY-15030) . Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively.

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  COX

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(C1=CC2=C(C=C1)C=C(C=C2)O[13C]([2H])([2H])[2H])C)=O

• Molecular Formula :

  C13 13CH11D3O3

• Molecular Weight :

  234.27

• Precautions :

  P264-P270-P330-P405-P501

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1261392-52-2]