Products for Research Use Only
RegisterLogin

MHTT-IN-1

CAT: 0804-HY-150245Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-150245Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD) . mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].
CAS Number
2839311-21-4
UNSPSC
12352005
Target
Huntingtin
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mhtt-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=NN3C=C(C)N=C3C(C)=C2)N=C4SC(N5CCNCC5)=CN14
Molecular Formula
C18H19N7OS
Molecular Weight
381.45
References & Citations
[1]Brom, et al. Preparation of thiazolopyrimidinone derivatives and uses thereof. World Intellectual Property Organization, WO2022194801 A1. 2022-09-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-156103-01MHTT-IN-2
HY-130258-01LC3-mHTT-IN-AN1
HY-130259-01LC3-mHTT-IN-AN2
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5
HY-133630-011-Bromo-1,1-dichloroacetone
HY-W881439-011- (1,1-Dimethylethyl) tridecanedioate

Alternative Products

CatalogName
GTR19212243-01MHTT-IN-1
T79717MHTT-IN-2
GTR19157072-01LC3-mHTT-IN-AN1
T5070-01LC3-mHTT-IN-AN2
A22054-10LC3-mHTT-IN-AN1 10mg
A22054-50LC3-mHTT-IN-AN1 50mg
A22054-25LC3-mHTT-IN-AN1 25mg
A22054-100LC3-mHTT-IN-AN1 100mg
A22054-5LC3-mHTT-IN-AN1 5mg

Popular Products