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Antibacterial agent 116

CAT: 0804-HY-150063Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-150063Size:1 Each
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Description
Antibacterial agent 116 is a benzophenone-containing salicylanilide compound. Antibacterial agent 116 has potent antibacterial activity by inhibiting the peptidoglycan formation. Antibacterial agent 116 is used as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), block the propagation pathway to disrupt the growth of peptidoglycan chain[1].
CAS Number
99330-28-6
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Bacterial; Penicillin-binding protein (PBP)
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-116.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C(I)=CC(I)=C1)O)NC2=CC(C(C3=CC=C(C=C3)Cl)=O)=CC=C2OC4=CC=C(C=C4)Cl
Molecular Formula
C26H15Cl2I2NO4
Molecular Weight
730.12
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Chuang HC, et al. Photoaffinity labeling of benzophenone-containing salicylanilide compounds to give an insight into the mechanism in disrupting peptidoglycan formation. Bioorg Med Chem. 2022 Aug 1;67:116819.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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