Mps1-IN-6

• UNSPSC Description:

  Mps1-IN-6 is a potent Mps1 inhibitor with an IC50 value of 2.596 nM. Mps1-IN-6 shows antiproliferative activity. Mps1-IN-6 shows antitumor activity[1].

• Target Antigen:

  Mps1

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mps1-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCC1=CC=CC(CC)=C1N2CCN3C=C(C=C3C2=O)C4=C5C=NNC5=NC(NC6=C(C=C(C=C6)N7CCN(CC7)C(C)=O)OC)=N4

• Molecular Weight:

  633.74

• References & Citations:

  [1]Shihe Hu, et al. Discovery of pyrazolo[3,4-b]pyridine derivatives as novel and potent Mps1 inhibitors for the treatment of cancer. European Journal of Medicinal Chemistry. 2023, 253: 115334.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3043761-59-4