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MGAT2-IN-4

CAT: 0804-HY-149893Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149893Size:1 Each
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Description
MGAT2-IN-4 (compound 33) is an inhibitor of monoacylglycerol transferase 2 (MGAT2), with liver metabolic stability. MGAT2-IN-4 can be used for research on obesity, diabetes and non-alcoholic steatohepatitis (NASH) [1].
CAS Number
1841424-92-7
UNSPSC
12352005
Target
Acyltransferase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mgat2-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C2=CC=C(C3=CCC(C)(CC3)C)C=C2)=CC(C4=CC=C(C)C=C4)=C1C5=NN=NN5
Molecular Formula
C27H27N5O
Molecular Weight
437.54
References & Citations
[1]Moore F, et al. Discovery of novel pyridinones as MGAT2 inhibitors for the treatment of metabolic disorders. Bioorg Med Chem Lett. 2023 Jul 15;91:129362.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported