Npx-Au

CAT: 0804-HY-149879Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-149879Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Npx-Au is a NSAID–Au (I) complex with antitumor activity. Npx-Au can be used for the research of ovarian cancer[1]. Npx-Au is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CAS Number

3036175-27-3

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/npx-au.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H](C1=CC2=C(C=C1)C=C(OC)C=C2)C)NCC#C[Au][P](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C35H31AuNO2P

Molecular Weight

725.57

References & Citations

[1]He Q, et al. Near-Infrared-Activatable PROTAC Nanocages for Controllable Target Protein Degradation and On-Demand Antitumor Therapy. J Med Chem. 2023 Jun 6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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