B3GNT2-IN-1

CAT: 0804-HY-149777-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-149777-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

B3GNT2-IN-1 (compound 8j) is a β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) inhibitor, with an IC50 of 9 nM[1].

CAS Number

3033557-95-5

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/b3gnt2-in-1.html

Purity

99.56

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C1NC2=CC=C(C=C2N1[C@@H](C(C)(C)C)C)C(N[C@@](C3=CN=C(N=C3)C(F)(F)F)4C)=NC4=O

Molecular Formula

C22H23F3N6O2

Molecular Weight

460.45

References & Citations

[1]Jackson JJ, et al. Imidazolone as an Amide Bioisostere in the Development of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors. J Med Chem. 2023 Dec 14;66 (23) :16120-16140.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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GTR19261497-01	B3GNT2-IN-1
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