ICMT-IN-12

ICMT-IN-12

• CAS Number: 1313603-25-6
• UNSPSC Description: ICMT-IN-12 (compound 78) is an inhibitor of ICMT (IC50=0.42 μM)[1].
• Target Antigen: ICMT
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/icmt-in-12.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C1)(C)SC(C)(C)CC1(CCNC2=CC(OC)=CC=C2)C3=CC=CC=C3
• Molecular Weight: 383.59
• References & Citations: [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported