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CDK9-IN-29

CAT: 0804-HY-149641Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149641Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK9-IN-29 (compound Z11) is a potent CDK9 inhibitor (IC50 = 3.20 nM) with good kinase selectivity. CDK9-IN-29 inhibits cell proliferation and induces apoptosis[1].
CAS Number
2737262-24-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-29.html
Solubility
10 mM in DMSO
Smiles
FC1=C(C=C(C=C1)C2=C(C=NC(N3)=N2)F)OCCCCCCOC4=CC3=CC=C4C(NCCN5CCOCC5)=O
Molecular Formula
C29H33F2N5O4
Molecular Weight
553.60
References & Citations
[1]Tizhi Wu, et al. Discovery of Selective and Potent Macrocyclic CDK9 Inhibitors for the Treatment of Osimertinib-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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