MMP13-IN-5

MMP13-IN-5

• UNSPSC Description: MMP13-IN-5 (compound 13m) is a potent and selective inhibitor of MMP-2/MMP-13 (IC50=3.6 μM/14.6 μM)，involved in osteoarthritis (OA)[1].
• Target Antigen: MMP
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/mmp13-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N/N=C/C1=CC=C(CNC(C2=CC=C(Br)O2)=O)C=C1)CC3=CC=C(C(O)=O)C=C3
• Molecular Weight: 484.30
• References & Citations: [1]Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported