Products for Research Use Only
RegisterLogin

MMP13-IN-2

CAT: 0804-HY-122624-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-122624-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research[1].
CAS Number
935759-55-0
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mmp13-in-2.html
Purity
99.13
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C(NC1=C2C(C3=CC=CC(F)=C3)=CS1)=NC2=O)NCC4=CC=CC(OCCOC5=NC=NN5)=C4
Molecular Formula
C24H19FN6O4S
Molecular Weight
506.51
References & Citations
[1]Hiroshi Nara, et al. Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP) -13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach. J Med Chem. 2017 Jan 26;60 (2) :608-626.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-13; MMP-2; MMP-3

Related Products

CatalogName
HY-149377MMP13-IN-4
HY-149378MMP13-IN-5
HY-P86592-01MMP13 Antibody (YA6284, Rabbit)
HY-P83398-01MMP13 Antibody (YA3143, Rabbit)
HY-RS08527Mmp13 Rat Pre-designed siRNA Set A
HY-RS08526Mmp13 Mouse Pre-designed siRNA Set A
HY-RS08525MMP13 Human Pre-designed siRNA Set A
HY-155071MmpL3-IN-2
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol

Alternative Products

CatalogName
BA8033-5MMP13-IN-2
377510MMP13
MBS7058158-01Recombinant Dog MMP13 protein (MMP13)
AP74527-01Recombinant Dog MMP13 protein(MMP13)
70R-11893MMP13 antibody
XYB17337MMP13-IN-3
T78775-01MMP13-IN-5
T78774-01MMP13-IN-4
DF6494-BPMMP13 Peptide

Popular Products