Acryl42-10

CAT: 0804-HY-149320Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-149320Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Acryl42-10 is a covalent inhibitor of the SARS-CoV-2 Nsp14 N7-Methyltransferase (IC50: 7 μM) [1].

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/acryl42-10.html

Solubility

10 mM in DMSO

Smiles

C=CC(NCC(OC)C(N1CCC(C2C(NC3=C2C=CC(Cl)=C3)=O)CC1)=O)=O

Molecular Formula

C20H24ClN3O4

Molecular Weight

405.88

References & Citations

[1]Singh I, et al. Structure-Based Discovery of Inhibitors of the SARS-CoV-2 Nsp14 N7-Methyltransferase. J Med Chem. 2023 Jun 22;66 (12) :7785-7803.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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