Products for Research Use Only
RegisterLogin

PptT-IN-4

CAT: 0804-HY-149305Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-149305Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PptT-IN-4 (Compound 3a) is a PptT inhibitor (IC50: 0.71 μM) . PptT-IN-4 inhibits Mtb H37Rv with a MIC value of 42 μM. PptT-IN-4 also inhibits hERG, hCav1.2, and hNav1.5 channels with IC50s of 11 μM, 8.1 μM, 6.9 μM respectively[1].
CAS Number
2948309-57-5
UNSPSC
12352005
Target
Bacterial; Calcium Channel; Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pptt-in-4.html
Solubility
10 mM in DMSO
Smiles
CCC1=C(NC2=CC=CC(NCC)=N2)C(CC)=CC=C1
Molecular Formula
C17H23N3
Molecular Weight
269.38
References & Citations
[1]Ottavi S, et al. Mycobacterium tuberculosis PptT Inhibitors Based on Heterocyclic Replacements of Amidinoureas. ACS Med Chem Lett. 2023 Jun 26;14 (7) :970-976.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-115882PptT-IN-1
HY-115883PptT-IN-2
HY-115884PptT-IN-3
HY-W099255-01Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate
HY-W7200064,4'-Diapo-ω, ω-carotene-4,4'-dial
HY-77910-014- (4-Bromophenyl) -4-hydroxypiperidine
HY-W0142264,4'-Dihydroxybenzophenone
HY-N90384',4''-Dihydroxyanigorootin
HY-W011927-014,4'-Sulfonyldiphenol
HY-W2697474,4'-Dimethoxyoctafluorobiphenyl

Alternative Products

CatalogName
MBS5820376PptT-IN-4
T61167-01PptT-IN-1
T61847-01PptT-IN-2
GTR19187076-01PptT-IN-3
M15469PptT inhibitor 8918
GTR18776689-01PptT Polyclonal Antibody
ARO-A22220-01Anti-pptT Polyclonal Antibody
PX-P1124-100Mycobacterium PptT Recombinant Protein
ARO-P18482-01PptT Recombinant Protein, N-His
GTR19146477-01Recombinant pptT Protein, N-His

Popular Products