BIBD-124

• Description :

  BIBD-124 binds amyloid beta (Aβ) plaque with an IC50 value of 9.51 nM. [18F]BIBD-124 can be used as radiotracer of Aβ plaques[1].

• UNSPSC :

  12352005

• Target :

  Amyloid-β

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/bibd-124.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CNC1=CC=C(C=N1)/C=C/C2=CN=C(C=C2)OCCOCCOCCF

• Molecular Formula :

  C19H24FN3O3

• Molecular Weight :

  361.41

• References & Citations :

  [1]Zheng W, et al. Synthesis and In Vitro and In Vivo Evaluation of 18F-Labeled Positron Emission Tomography Tracers for Imaging Aβ Plaques. ACS Chem Neurosci. 2023 Mar 1;14 (5) :988-1003.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2716871-93-9]