D-685

CAT: 0804-HY-149065Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149065Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
D-685, a prodrug of D-520, exhibits higher in vivo anti-Parkinsonian efficacy in a reserpinized Parkinson's disease (PD) animal model than the parent D-520. D-685 reduces accumulation of human α-synuclein (α-syn) protein. D-685 exhibits facile brain penetration[1].
CAS Number
[2893801-00-6]
UNSPSC
12352005
Target
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-685.html
Solubility
10 mM in DMSO
Smiles
OC1=C2CC[C@H](N(CCN3CCN(C4=CC=C(C5=CC=C(OCO6)C6=C5)C=C4)CC3)CCC)CC2=CC=C1
Molecular Formula
C32H39N3O3
Molecular Weight
513.67
References & Citations
[1]Aloke K Dutta, et al. D-685 Reverses Motor Deficits and Reduces Accumulation of Human α-Synuclein Protein in Two Different Parkinson's Disease Animal Models. ACS Chem Neurosci. 2023 Mar 1;14 (5) :885-896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
α-synuclein Aggregation

Related Products

CatalogName
HY-173571TK-685
HY-122268QYL-685
HY-W1008879CRBN ligand-685
HY-W018772S6-01D-Ribose-d
HY-N0379S11-01D-Mannose-d
HY-N9914S-01D-Psicose-d
HY-128753S6-01D-Lyxose-d
HY-N7092S8-01D-Fructose-d
HY-P4549H-D-Ala-D-Ala-D-Ala-D-Ala-OH
HY-P3881(D-Arg1, D-Pro2, D-Phe7, D-His9) -Substance P

Alternative Products

CatalogName
MF-0146810-01D-685
MF-0138395-01QYL-685
MF-0117865-01TK-685
MBS131312LJH-685
ABC-TC0164COLO-685
sc-204042AL-685,458
MBS3608373-01L-685, 458
GT17671Spark NIR™ 685 Streptavidin
1713-250EZSolution™ L-685,458
8B8278-AATGRK2 (Ab-685) Antibody

Popular Products