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PAA4

CAT: 0804-HY-149035Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149035Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAA4 is a methide carbon-centered polynuclear Au (I) clusters. PAA4 shows antiproliferative activity. PAA4 increases the expression of pH2AX in a time dependent manner. PAA4 shows anti-tumor effect in orthotopic bladder cancer mouse model[1].
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/paa4.html
Solubility
10 mM in DMSO
Smiles
[F-][B+3]([F-])([F-])[F-].C1(C(C234[Au]5[Au]2[Au]3[Au]45)=NC6=C7C=CC=C6)=C7C=CC=C1
Molecular Formula
C14H8Au4BF4N
Molecular Weight
1064.89
References & Citations
[1]Xiao K, et al. Pro-oxidant response and accelerated ferroptosis caused by synergetic Au (I) release in hypercarbon-centered gold (I) cluster prodrugs. Nat Commun. 2022 Aug 9;13 (1) :4669.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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