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SLF1081851 (TFA)

CAT: 0804-HY-149004ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149004ASize:1 Each
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Description
SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM) . SLF1081851 (TFA) plays a key role in development and immune system[1][2].
CAS Number
2763730-98-7
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/slf1081851-tfa.html
Solubility
10 mM in DMSO
Smiles
NCCCC1=NC(C2=CC=C(CCCCCCCCCC)C=C2)=NO1.O=C(O)C(F)(F)F
Molecular Formula
C23H34F3N3O3
Molecular Weight
457.53
References & Citations
[1]Fritzemeier R, et al. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2022 Jun 9;65 (11) :7656-7681. |[2]Lynch Kevin R, et al. Preparation of oxadiazoles as inhibitors of spinster homolog 2 (SPNS2) for use in therapy: World Intellectual Property Organization, WO2022056042[P]. 2022-03-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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