PI3Kα-IN-7
CAT:
804-HY-149000
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PI3Kα-IN-7
- CAS Number: 2417098-53-2
- UNSPSC Description: PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor. PI3Kα-IN-7 also inhibits PI3Kβ. PI3Kα-IN-7 decreases cancer cells mitochondrial membrane potential and induces apoptosis[1].
- Target Antigen: Apoptosis; PI3K
- Type: Reference compound
- Related Pathways: Apoptosis;PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pi3kα-in-7.html
- Solubility: 10 mM in DMSO
- Smiles: C1(NCC2=CC(N=C(N3CCOCC3)N=C4N5CCOCC5)=C4S2)=NNC=N1
- Molecular Weight: 402.47
- References & Citations: [1]Ye T, et al. Design, synthesis and biological evaluation of novel 2,4-bismorpholinothieno[3,2-d]pyrimidine and 2-morpholinothieno[3,2-d]pyrimidinone derivatives as potent antitumor agents. Bioorg Chem. 2020 Jun;99:103796.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported