q-FTAA

• UNSPSC Description:

  q-FTAA binds to Aβ1-42 fibrils with EC50 values of 330-630, 300-500 nM for Aβ1-42 fibrils, alzheimer's disease PIB binding complex (ADPBC) , respectively. q-FTAA has the potential for the research of Alzheimer's disease (AD)[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/q-ftaa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C2=CC(CC(O)=O)=C(C3=CC=C(C4=C(CC(O)=O)C=CS4)S3)S2)S1)O

• Molecular Weight:

  490.59

• References & Citations:

  [1]Bäck M, et al. Anionic Oligothiophenes Compete for Binding of X-34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ. Chemistry. 2016 Dec 19;22(51):18335-18338.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1352477-22-5