Products for Research Use Only
RegisterLogin

H-FTAA

CAT: 0804-HY-177906Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-177906Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
H-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as Aβ plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Aβ plaques[1][2].
CAS Number
1352477-26-9
UNSPSC
12352100
Target
Amyloid-β; Fluorescent Dye
Related Pathways
Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(C1=CC=C(C2=CC=C(C3=CC(CC(O)=O)=C(C4=CC=C(C5=C(CC(O)=O)C=C(C6=CC=C(C7=CC=C(C(O)=O)S7)S6)S5)S4)S3)S2)S1)O
Molecular Formula
C34H20O8S7
Molecular Weight
780.97
References & Citations
[1]Sandin L, et al. The Luminescent Conjugated Oligothiophene h-FTAA Attenuates the Toxicity of Different Aβ Species. Biochemistry. 2021 Sep 21;60 (37) :2773-2780.|[2]Wood JI, et al. Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer's disease mouse model. Nat Commun. 2025 Sep 1;16 (1) :8170.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-148547-01Q-FTAA
HY-P10908-01H-20
HY-N16670Sorocein H
HY-N15477Nanangenine H
HY-N14499Saframycin H
HY-N13948Argyrin H
HY-N16144Osmanthuside H
HY-P1122-01Cyclosporin H
HY-N13928Arisugacin H
HY-N9074Shizukanolide H

Alternative Products

CatalogName
GTR19212059-01Q-FTAA
sc-58703H-Caldesmon (h-CALD)
sc-75218H-prune siRNA (h)
sc-29340-PRH-Ras (h) -PR
sc-75218-PRH-prune (h) -PR
sc-37565-PRCENP-H (h) -PR
sc-166613Factor H (H-7)
sc-92053-PROATP-H (h) -PR
sc-37565CENP-H siRNA (h)
sc-101013HCAP-H (H-6)

Popular Products