METTL3-IN-2

• UNSPSC Description:

  METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].

• Target Antigen:

  METTL3

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mettl3-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CN2C(C(C3=CN(CC4=CN5C(C=CC(CNCC6(C7)CC7C6)=C5)=N4)N=N3)=C1)=CN=C2

• Molecular Weight:

  454.53

• References & Citations:

  [1]Hardick, DJ, et al. Preparation of heteroaromatic compounds as METTL3 inhibitory compounds. WO2022074379. 2022.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2767258-88-6