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SphK1-IN-3

CAT: 0804-HY-148262Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-148262Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SphK1-IN-3 is an effective sphingosine kinase-1 (SphK1) inhibitor. SphK1-IN-3 inhibits SphK1 kinase activity with an IC50 value of 2.48 μM. SphK1-IN-3 can be used for the research of many diseases such as cancer, rheumatoid arthritis, diabetes, asthma, and pulmonary fibrosis[1].
UNSPSC
12352005
Target
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sphk1-in-3.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC=C2NC(C3=C(N4CCOCC4)N(C5=CC=CC=C5)N=C3C)=NC2=C1)[O-]
Molecular Formula
C21H20N6O3
Molecular Weight
404.42
References & Citations
[1]Shadia A. Galal, et al. Design and synthesis of new pyrazolylbenzimidazoles as sphingosine kinase-1 inhibitors. Med Chem Res 30, 1614–1634 (2021) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SphK1

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