ACC1/2-IN-2

ACC1/2-IN-2

• CAS Number: 1031411-94-5
• UNSPSC Description: ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 has antiproliferation activity and can be used for cancer research[1].
• Target Antigen: Acetyl-CoA Carboxylase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/acc1-2-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15
• Molecular Weight: 403.47
• References & Citations: [1]Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported