ACC1/2-IN-2

• UNSPSC Description:

  ACC1/2-IN-2 (compound PF-3) is a potent ACC1/2 inhibitor with IC50 values of 22 and 48 nM for ACC1 and ACC2, respectively. ACC1/2-IN-2 has antiproliferation activity and can be used for cancer research[1].

• Target Antigen:

  Acetyl-CoA Carboxylase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/acc1-2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1CC2(CCN(C(C3=CC4=C(NN=C4)C(C)=C3)=O)CC2)OC5=CC(C)=C(C)C=C15

• Molecular Weight:

  403.47

• References & Citations:

  [1]Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1031411-94-5