ACC1/2-IN-1

• Description :

  ACC1/2-IN-1 (compound 4s) is a potent ACC1/2 inhibitor with IC50 values of 98.06 and 29.43 nM for ACC1 and ACC2, respectively. ACC1/2-IN-1 can be used for cancer research[1].

• UNSPSC :

  12352005

• Target :

  Acetyl-CoA Carboxylase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/acc1-2-in-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(O2)C=C3C(CCC(C)(C)O3)=C1)CC42CCN(C(C5=CC=C6NC(C7=CC8=C(NC=C8)C=C7)=NC6=C5)=O)CC4

• Molecular Formula :

  C34H32N4O4

• Molecular Weight :

  560.64

• References & Citations :

  [1]Wei Q, et al. Design, synthesis and biological evaluation of novel chroman derivatives as non-selective acetyl-CoA carboxylase inhibitors. Bioorg Chem. 2020 Aug;101:103943.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2350219-22-4]