PI3K-IN-34

PI3K-IN-34

• CAS Number: 2458163-94-3
• UNSPSC Description: PI3K-IN-34 (Compound 6g) is a highly selective PI3K inhibitor with IC50 values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-34 arrests cell cycle at G2/M phase and induces apoptosis. PI3K-IN-34 can be used in leukemia research[1].
• Target Antigen: Apoptosis; PI3K
• Type: Reference compound
• Related Pathways: Apoptosis;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3k-in-34.html
• Solubility: 10 mM in DMSO
• Smiles: N#CC1=C(N2CCOCC2)N=C(N/N=C/C3=CC=CC(O)=C3)N=C1C4=CC=C(OC)C=C4
• Molecular Weight: 430.46
• References & Citations: [1]Helwa AA, et al. Novel antiproliferative agents bearing morpholinopyrimidine scaffold as PI3K inhibitors and apoptosis inducers; design, synthesis and molecular docking. Bioorg Chem. 2020 Sep;102:104051.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported