Aldose reductase-IN-6
CAT:
804-HY-147875
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Aldose reductase-IN-6
- CAS Number: 2470019-41-9
- UNSPSC Description: Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki of 0.018 μM. Aldose reductase-IN-6 exhibits no cytotoxicity against healthy cells[1].
- Target Antigen: Aldose Reductase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/aldose-reductase-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: N#CC1=CC=C(C2=CSC(N/N=C/C3=CC=C(OCCCO4)C4=C3)=N2)C=C1
- Molecular Weight: 376.43
- References & Citations: [1]Sever B, et al. Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds. Bioorg Chem. 2020 Sep;102:104110.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported