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Antibacterial agent 106

CAT: 0804-HY-147531Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147531Size:1 Each
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Description
Antibacterial agent 106 (compound 8) is an orally active and potent antibacterial agent with antibiofilm activity. Antibacterial agent 106 shows potent antibacterial effect against multi-agent resistant (MDR) -Gram positive pathogens. Antibacterial agent 106 is highly effective in clearing 99.7% of the intracellular methicillin-resistant S. aureus (MRSA) harbored inside macrophages[1]. Antibacterial agent 106 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2459657-11-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-106.html
Solubility
10 mM in DMSO
Smiles
CC1=C(SC(C2=CC=C(C=C2)C#CCCN3CCC3)=N1)/C(C)=N/NC(N)=N
Molecular Formula
C20H24N6S
Molecular Weight
380.51
References & Citations
[1]Hosny Y, et al. Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. Eur J Med Chem. 2020 Jan 1;185:111830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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