hCAII-IN-3

• UNSPSC Description:

  hCAII-IN-3 (Compound 16) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 403.8, 5.1, 10.2 and 5.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-2 shows anticancer activity[1].

• Target Antigen:

  Carbonic Anhydrase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hcaii-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NS(=O)(C1=CC=C(C=C1)NCC/C(C2=CC=CC=C2)=N/CCO)=O

• Molecular Weight:

  347.43

• References & Citations:

  [1]Elbadawi MM, et al. Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Apr 27;238:114412.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2770927-76-7