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HCAII-IN-3

CAT: 0804-HY-146008Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146008Size:1 Each
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Description
HCAII-IN-3 (Compound 16) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 403.8, 5.1, 10.2 and 5.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-2 shows anticancer activity[1].
CAS Number
2770927-76-7
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaii-in-3.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)NCC/C(C2=CC=CC=C2)=N/CCO)=O
Molecular Formula
C17H21N3O3S
Molecular Weight
347.43
References & Citations
[1]Elbadawi MM, et al. Development of 4- ((3-oxo-3-phenylpropyl) amino) benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Apr 27;238:114412.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA IX; CA XII

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