hCAII-IN-3

hCAII-IN-3

• CAS Number: 2770927-76-7
• UNSPSC Description: hCAII-IN-3 (Compound 16) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 403.8, 5.1, 10.2 and 5.2 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-2 shows anticancer activity[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcaii-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: NS(=O)(C1=CC=C(C=C1)NCC/C(C2=CC=CC=C2)=N/CCO)=O
• Molecular Weight: 347.43
• References & Citations: [1]Elbadawi MM, et al. Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2022 Apr 27;238:114412.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported