GSD-11

• UNSPSC Description:

  GSD-11 is a potent and selective anti-austerity agent. GSD-11 inhibits the cell migration and colony formation of PANC-1 cells. GSD-11 inhibits the Akt/mTOR signaling pathway. GSD-11 has the potential for the research of pancreatic cancer[1].

• Target Antigen:

  Akt

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/gsd-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@@]12CC[C@]3([C@@]4(CC(C([C@]4(CC[C@@]3([C@]1(CCC(C2)=O)C)[H])C)=C)=O)[H])[H]

• Molecular Weight:

  300.44

• References & Citations:

  [1]Kohyama A, et al. Structure-activity relationship and mechanistic study on guggulsterone derivatives; Discovery of new anti-pancreatic cancer candidate. Bioorg Med Chem. 2022; 54:116563.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported