PqsR-IN-2

• UNSPSC Description:

  PqsR-IN-2 (Compound 19) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pqsr-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCCCC1=NC(CN2C=NC3=CC=C(C=C3C2=O)Cl)=CS1

• Molecular Weight:

  361.89

• References & Citations:

  [1]Scott Grossman, et al. Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR. Eur J Med Chem. 2020 Dec 15;208:112778.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2982271-63-4