PqsR-IN-3

• Target:

  Antibacterial

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 ?M) and its associated virulence factor pyocyanin (IC50=2.7 ?M) . This compound inhibits the synthesis of bacterial biofilms and is significantly cytotoxic to Pseudomonas aeruginosa. Additionally, PqsR-IN-3 exhibits synergistic effects with various antibiotics, such as Ciprofloxacin and Tobramycin.

• Smiles:

  O=C1C=C(N(C(=C1O)CNCC=2N=NN(C2)C3=CC=C(OC=4C=CC=CC4)C=C3)C)C

• Molecular Formula:

  C23H23N5O3

• Molecular Weight:

  417.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033007-79-0