hCAI/II-IN-1

hCAI/II-IN-1

• CAS Number: 2422028-82-6
• UNSPSC Description: hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor with IC50 values of 0.047 µM and 0.024 µM against hCA I and hCA II, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcai-ii-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CN(CCCN1CCN(CC1)C(SCC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)=S)C
• Molecular Weight: 459.65
• References & Citations: [1]Sağlık BN, et al. Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate. Eur J Med Chem. 2020 Jul 15;198:112392.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported